Clinical Trials & Research
Where science, safety, and support meet real people.
At Psychedelic Science Institute, clinical trials are at the heart of our work.
Every study we conduct is designed to bring safe, effective psychedelic therapies to the people who need them most. Our research addresses real-life mental health challenges for which current treatments often fall short — including major depression, anxiety, PTSD, and addiction — and we plan to expand to neurological conditions like traumatic brain injury, stroke, dementia and chronic pain.
This is how psychedelic medicine earns its future: with rigorous science, participant-centered care, and a commitment to equity at every step.
Whether you're exploring treatment options, referring a patient, or looking to partner in research, PSI is the place to begin the process.
Clinical Trials
See what trials are currently enrolling or in progress, and how they’re helping move therapies like psilocybin, LSD, MDMA, DMT, and 5-MeO-DMT into FDA-approved treatments.
What is the uASPIRE Study? The purpose of this clinical research study is to determine the safety and effectiveness of treatment with psilocybin in adults diagnosed with major depressive disorder (MDD). Currently available treatments for depression may not work for everyone, so alternative treatments are being sought through clinical research studies.
Feeling down despite antidepressants? Learn more about our research study for an investigational medicine for treatment-resistant depression.
Participating in a Clinical Trial
Interested in joining a study? We’ll walk you through what to expect, who’s eligible, and how we support you before, during, and after your sessions.
For Industry Sponsors & Collaborators
Learn why leading psychedelic biotech companies trust PSI as a high-integrity research site, and how we’re built for scalable, participant-centered studies.
Peer-Reviewed Publications by PSI Team
Explore published studies, results, and peer-reviewed insights from our team and the clinical trials in which we have participated.
